Surgery>>>>>Thoracic Aneurysms and Aortic Dissection
Question 2#

Which of the following is the most common cause of thoracic aortic aneurysms?

a. Atherosclerosis
b. Marfan syndrome
c. Takayasu arteritis
d. Nonspecific medial degeneration

Correct Answer is D


Nonspecific medial degeneration is the most common cause of thoracic aortic disease. Histologic findings of mild medial degeneration, including fragmentation of elastic fibers and loss of smooth muscle cells, are expected in the aging aorta. However, an advanced, accelerated form of medial degeneration leads to progressive weakening of the aortic wall, aneurysm formation, and eventual dissection, rupture, or both. The underlying causes of medial degenerative disease remain unknown.