Surgery>>>>>Small Intestine
Question 18#

Adenocarcinoma of the duodenum is associated with what hereditary oncologic syndrome?

A. Hereditary nonpolyposis colorectal cancer (HNPCC)
B. Familial adenomatous polyposis (FAP)
C. Peutz-Jeghers syndrome
D. Von Hippel-Lindau (VHL) syndrome

Correct Answer is B

Comment:

Duodenal carcinoma is a late manifestation of the familial adenomatous polyposis (FAP) syndrome. After resolution of the colonic disease by total colectomy, patients with FAP must be followed with periodic upper gastrointestinal ( GI) endoscopy to maintain surveillance for duodenal tumors. Duodenal cancer is the leading cause of death among patients with FAP.