Surgery>>>>>Small Intestine
Question 19#

Which of the following statements is true regarding GISTs?

A. Most occur in the small intestine
B. GISTs are usually metastatic when first diagnosed
C. GISTs typically present with GI hemorrhage
D. GISTs are usually responsive to cytotoxic chemotherapy

Correct Answer is C

Comment:

GISTs are a form of sarcoma which occur most commonly (70%) in the stomach. They more frequently present with GI hemorrhage than other small bowel malignancies. They are usually refractory to conventional cytotoxic chemotherapy, but are not usually metastatic on initial diagnosis. A radical lymphadenectomy is not usually required; a segmental resection of the involved portion of the small intestine is usually sufficient surgical treatment.