Plastic Surgery>>>>>Cutaneous malignancy and sarcoma
Question 6#

The following are histopathological terms correctly matched with their meanings:

A. Parakeratosis: where nucleated cells are found in the superficial epidermis
B. Maturation: where naevocellular naevi become more superficially cited in the epidermis
C. Peripheral pallisading: a feature of poorly differentiated squamous carcinoma
D. Erythroplakia - red lesions of the oral mucosa
E. Leukoplakia - white lesions of the oral mucosa

Correct Answer is A

Comment:

Parakeratosis: where nucleated cells are found in the superficial epidermis. Parakeratosis is where nuclei of keratinocytes persist as they rise into the horny layer of the skin; it occurs normally in the epithelium of mucous membranes. When it occurs on the external skin it constitutes a lesion. Maturation is where naevus cells migrate into the dermis. Peripheral pallisading is classically seen in basal carcinoma and occasionally ‘basi-squamous’ carcinoma (a controversial diagnosis). Neither erythroplakia nor leukoplakia are histopathological terms - they denote clinical appearances, although they are both correctly defined.