Urology>>>>>Basic Science and Molecular Oncology
Question 3#

Which of the following represents a premalignant process where abnormal cytological and architectural changes lead to disordered growth and maturation of a cell?

a. Teratoma
b. Metaplasia
c. Dysplasia
d. Atrophy
e. Hyperplasia

Correct Answer is C


Answer C

Dysplasia is a pre-malignant condition where there is abnormal cell growth, cellular atypia and abnormal differentiation. It can be a reversible process in its early stage but once it becomes severe it can progress to neoplasia. Metaplasia a process where one type of differentiated cell transforms into another differentiated cell type. This process is reversible. It is an adaptive response of a tissue to changes in the environment so that the tissue can withstand these changes.