The following are TRUE about Klinefelter’s syndrome except:
A. Affected male has 47, XXY genotypeAnswer D
The Klinefelter’s syndrome is the most frequent sex chromosome abnormality. Testosterone levels may be normal or low. Germ cell presence and sperm production are variable in men with Klinefelter’s mosaicism, 46,XY/47,XXY. These patients have 50 times higher risk of germ cell tumours which usually contains non-seminomatous germ cells and present at an earlier age and seldom are gonadal in location.