Question 5#

Each line in Figure below 

Relationship between drug concentration and effect.

represents a β-blocker in development. Which βblocker is the most potent?

A. A
B. B
C. C
D. Potency cannot be determined from the above graph

Correct Answer is A


a. Drug A is the most potent agent. This is based on the fact that at any given concentration of this agent, the effect is greater than that of the other drugs at similar concentrations. Drug B has the same maximal effect; however, it occurs at a higher concentration. Drug C is similar to drug B; however, it is less efficacious, because its maximal effect occurs at a concentration that is 50% lower than that of drug B.