Which of the following factors are suggestive of a hereditary cancer?
a. Tumor development at a younger than normal age b. Presence of bilateral disease c. Association with paraneoplastic syndrome d. Presence of multiple primary malignancies
Correct Answer is C
Comment:
The following factors may suggest the presence of a hereditary cancer:
Tumor development at a much younger age than usual.
Presence of bilateral disease.
Presence of multiple primary malignancies.
Presentation of a cancer in the less affected sex ( eg, male breast cancer).
Clustering of the same cancer type in relatives.
Occurrence of cancer in association with other conditions such as mental retardation or pathognomonic skin lesions.