Question 6#

Which of the following are associated with familial adenomatous polyposis (FAP):

A) Osteomas
B) Glioblastoma multiforme
C) Meckel diverticulum
D) Esophageal atresia

Correct Answer is A


Familial adenomatous polyposis (FAP) is associated with benign extracolonic manifestations that may be useful in identifying new cases, including congenital hypertrophy of the retinal pigment epithelium, epidermoid cysts, and osteomas. In addition to colorectal cancer, patients with FAP are at risk for upper intestinal neoplasms (gastric and duodenal polyps, duodenal and periampullary cancer), hepatobiliary tumors (hepatoblastoma, pancreatic cancer, and cholangiocarcinoma), thyroid carcinomas, desmoid tumors, and medulloblastomas.