Which mutated gene malignant disease association is correct:A) PTEN and Li-Fraumeni syndrome
MEN2 syndrome is caused by gain of function mutations in the RET gene. Li-Fraumeni syndrome is associated with mutation ofTP53. Mutations in pl6 is associated with melanomas, as well as cancers of the pancreas, esophagus, head and neck, stomach, breast, and colon. BRCAI is associated with breast and ovarian carcinoma.