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Category: Prometric--->Haematology/Oncology
Page: 26

Question 126# Print Question

A 71-year-old woman with no significant past medical history is investigated for lymphocytosis. She has recently lost 7kg in weight and complains of lethargy. The following blood results are obtained: 

  • Hb 9.8 g/dl
  • Plt 104 * 109/l
  • WBC 70.3 * 109/l
  • Blood film: Lymphocytosis. Smudge cells seen

Four months previously her white cell count was 30.5 * 109/l.

What is the most appropriate management?

A. Imatinib
B. Chlorambucil
C. No treatment, monitor full blood coun
D. Fludarabine, cyclophosphamide and rituximab
E. Allogeneic stem cell transplantation


Question 127# Print Question

What is the lifetime risk of developing colorectal cancer in the United Kingdom? 

A. 1%
B. 2%
C. 5%
D. 10%
E. 15%


Question 128# Print Question

Which one of the following is the most common inherited thrombophilia?

A. Protein S deficiency
B. Antithrombin III deficiency
C. Protein C deficiency
D. Activated protein C resistance
E. Von Willebrand's disease


Question 129# Print Question

Each one of the following is associated with polycythaemia rubra vera, except:

A. Splenomegaly
B. Hyperviscosity
C. Raised ESR
D. Hypertension
E. Pruritus


Question 130# Print Question

A 4-year-old girl with sickle cell anaemia presents with abdominal pain. On examination she is noted to have splenomegaly and is clinically anaemic.

What is the most likely diagnosis?

A. Liver cirrhosis
B. Parvovirus infection
C. Sequestration crisis
D. Salmonella infection
E. Thrombotic crisis




Category: Prometric--->Haematology/Oncology
Page: 26 of 28