A 31-year-old woman presents for review. For the past few months she has been feeling generally tired and has not had a normal period for around 4 months. Prior to this she had a regular 30 day cycle. A pregnancy test is negative, pelvic examination is normal and routine bloods are ordered:
What is the most likely diagnosis?
Correct Answer D:
Premature ovarian failure:
Premature ovarian failure is defined as the onset of menopausal symptoms and elevated gonadotrophin levels before the age of 40 years.
Causes:
Features are similar to those of the normal climacteric but the actual presenting problem may differ:
Which one of the following statements regarding epidemiological measures is correct?
Correct Answer A:
Incidence and prevalence: These two terms are used to describe the frequency of a condition in a population.
The incidence is:
The prevalence is:
Relationship:
Which one of the following adrenoceptors causes inhibition of pre-synaptic neurotransmitter release in response to sympathetic stimulation?
Correct Answer B:
Adrenoceptors:
Alpha-1:
Alpha-2:
Beta-1:
Beta-2:
Beta-3:
Pathways:
A 43-year-old man is suspected of having a common peroneal nerve palsy following a fracture of his fibula.
Each one of the following features may be seen in such lesions, except:
Correct Answer E: Sensory loss over the dorsum of the foot and the lower lateral part of the leg is seen in a common peroneal nerve palsy. The degree of wasting would of course depend on how long the nerve palsy had been present.
Common peroneal nerve lesion: The sciatic nerve divides into the tibial and common peroneal nerves. Injury often occurs at the neck of the fibula.
The most characteristic feature of a common peroneal nerve lesion is foot drop.
Other features include:
Which one of the following is involved in the translation of RNA into proteins?
Correct Answer C:
Cell organelles:
The table below summarizes the main functions of the major cell organelles: