Multiple Choice Questions (MCQ)

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Category: Cardiology--->Pharmacology
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Question 1# Print Question

P. M. is admitted to the coronary intensive care unit (ICU) with atrial fibrillation (AFib) and rapid ventricular rate. After controlling the ventricular rate with metoprolol, it is decided to initiate procainamide by intravenous (IV) infusion. P. M. weighs 80 kg. How much of a loading dose would be required to target a level of 8 μg/L? The average steady-state volume of distribution (Vd ) for procainamide is 2 L/kg. The bioavailability of the IV formulation is 100%, whereas the oral (PO) form is only 83%.

A. 1,000 mg
B. 1,300 mg
C. 1,500 mg
D. 1,700 mg

Question 2# Print Question

L. M. has been receiving digoxin 0.25 mg PO tablets daily. Her serum drug level is 1.8 ng/mL. She is no longer able to take PO medications and needs to receive digoxin IV. By what percentage do you need to decrease the dose to maintain the current digoxin level?

A. 10%
B. 25%
C. 40%
D. 50%

Question 3# Print Question

What two pharmacokinetic parameters alter the half-life of medications?

A. Loading dose and clearance
B. Absorption and clearance
C. Vd and clearance
D. Absorption and Vd

Question 4# Print Question

What is the relationship between drug concentration and pharmacologic effect known as?

A. Pharmacokinetics
B. Pharmacogenetics
C. Pharmacology
D. Pharmacodynamics

Question 5# Print Question

Each line in Figure below 

Relationship between drug concentration and effect.

represents a β-blocker in development. Which βblocker is the most potent?

A. A
B. B
C. C
D. Potency cannot be determined from the above graph

Category: Cardiology--->Pharmacology
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