Multiple Choice Questions (MCQ)

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Category: Surgery--->Systemic Response to Injury and Metabolic Support
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Question 1# Print Question

C-reactive protein (CRP)

A. Is secreted in a circadian rhythm with higher levels in the morning
B. Increases after eating a large meal
C. Does not increase in response to stress in patients with liver failure
D. Is less sensitive than erythrocyte sedimentation rate as a marker of inflammation

Question 2# Print Question

Which of the following is true regarding the inflammatory response following traumatic injury? 

A. There is an acute proinflammatory response caused by stimulation of the adaptive immune system
B. There is an anti-inflammatory response that leads to a return to homeostasis accompanied suppression of the innate immune system
C. The degree of inflammation is proportional to injury severity
D. Systemic inflammation following trauma is related to the immune response to microbes

Question 3# Print Question

High-mobility group protein B l (HMGB l )

A. I s associated with the best -characterized damageassociated molecular pattern (DAMP), detectable in the circulation within 30 minutes of trauma
B. Is a protein secreted by immune-competent cells stimulated by pathogen-associated molecular patterns (PAMPs) or inflammatory cytokines
C. Is also secreted by endothelial cells, platelets, and also as a part of cell death
D. All of the above

Question 4# Print Question

The most abundant amino acid in the human body is

A. Carnitine
B. Arginine
C. Glutamine
D. Methionine

Question 5# Print Question

What is the role of mitochondrial DAMPs in the injurymediated inflammatory response?

A. Mitochondrial DNA induces production ofHMGBl
B. Mitochondrial DNA and peptides from damaged mitochondria activate the macrophage inflammasome
C. Mitochondrial DNA and peptides modulate the anti-inflammatory response that suppresses the adaptive immune system
D. Mitochondrial DNA is directly toxic to the liver and lung in high amounts

Category: Surgery--->Systemic Response to Injury and Metabolic Support
Page: 1 of 2