Multiple Choice Questions (MCQ)

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Category: Prometric--->Haematology/Oncology
Page: 1

Question 1# Print Question

A 30-year-old man is investigated for enlarged, painless cervical lymph nodes. A biopsy is taken and a diagnosis of Hodgkin's lymphoma is made.

Which one of the following types of Hodgkin's lymphoma carries the best prognosis?

A. Lymphocyte predominant
B. Mixed cellularity
C. Nodular sclerosing
D. Hairy cell
E. Lymphocyte depleted

Question 2# Print Question

Which one of the following cytotoxic agents acts by inhibiting dihydrofolate reductase and thymidylate synthesis?

A. Methotrexate
B. Vincristine
C. Bleomycin
D. Cyclophosphamide
E. Doxorubicin

Question 3# Print Question

A 4-year-old boy is admitted after developing a haemarthrosis in his right knee whilst playing in the garden.

The following blood results are obtained:

  • Platelets 220 * 109/l
  • PT 11 secs
  • APTT 76 secs
  • Factor VIIIc activity Normal

What is the most likely diagnosis?

A. Antithrombin III deficiency
B. Von Willebrand's disease
C. Antiphospholipid syndrome
D. Haemophilia A
E. Haemophilia B

Question 4# Print Question

A 45-year-old woman is diagnosed with non-Hodgkin's lymphoma. She is a recovering alcoholic and has been left with significant alcohol-related peripheral neuropathy.

Which one of the following chemotherapy agents should be avoided if possible, given her past history?

A. Doxorubicin
B. Vincristine
C. Chlorambucil
D. Docetaxel
E. Cyclophosphamide

Question 5# Print Question

A 56-year-old man with metastatic prostate cancer comes for review. He is known to have spinal metastases but until now has not had any significant problems with pain control. Unfortunately he is now getting regular back pain despite taking paracetamol 1g qds. Neurological examination is unremarkable.

What is the most appropriate next step?

A. Switch to co-codamol 30/500
B. Refer for radiotherapy
C. Add oral bisphosphonate
D. Add diclofenac
E. Add dexamethasone

Category: Prometric--->Haematology/Oncology
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