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Category: Psychiatry--->Basic Statistics
Page: 2

Question 6# Print Question

The prevalence of depression in patients with mild cognitive impairment is 10%. On applying a depression rating scale with the likelihood ratio of a positive test (LR+) equal to 10, a patient with mild cognitive impairment becomes test positive.

The probability that this patient is depressed is equal:

A. 15%
B. 32%
C. 52%
D. 85%
E. 100%

Question 7# Print Question

A multi-centre double blind pragmatic randomized controlled trial (RCT) reported remission rates for depression of 65% for fluoxetine and 60% for dosulepin.

The number of patients that must receive fluoxetine for one patient to achieve the demonstrated beneficial effect is:

A. 60
B. 20
C. 15
D. 10
E. 5

Question 8# Print Question

In a randomized double-blind trial two groups of hospitalized depressed patients treated with selective serotonin reuptake inhibitors (SSRIs) are evaluated for beneficial effects on insomnia of trazodone vs temazepam.

Which of the following is NOT an important factor when evaluating the internal validity of results obtained from the above study?

A. Baseline differences in antidepressant therapy between the two groups
B. The method used to randomize the sample
C. Setting in which the study takes place
D. Sensitivity of the insomnia scale to pick up changes in severity
E. Inclusion of the data in final analysis from patients who have dropped out

Question 9# Print Question

While adapting the results of an RCT (Randomized Controlled Trial)  into clinical practice, a clinician wants to calculate the new NNT values for his own clinical population using the results of the RCT.

Apart from the reported RCT which of the following is needed to carry out the calculation of the new NNT (Number Needed to Treat)?

A. The expected rate of spontaneous resolution of the treated condition in the clinical population
B. The size of the clinical population
C. The case fatality rate for the treated condition in the clinical population
D. Lifetime prevalence of the disease in the clinical population
E. All of the above

Question 10# Print Question

In an attempt to ensure equivalent distribution of potential effect-modifying factors in treating refractory depression, a researcher weighs the imbalance that might be caused whenever an individual patient enters one of the two arms of the study. Every patient is assigned to the group where the least amount of imbalance will be caused.

This method is called:

A. Stratification
B. Matching
C. Minimization
D. Randomization
E. Systematic sampling

Category: Psychiatry--->Basic Statistics
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